Nitrate handling and glucose tolerance

Purpose

Researchers have recently shown that dietary nitrate (such as found in green leafy vegetables and beetroot) has several beneficial effects such as lowering blood pressure and improving exercise performance.  

Researchers from Guy's and St Thomas' and King's College London are now interested in looking at whether dietary nitrate improves the body’s ability to handle blood sugar levels.

Who can take part?

To be considered for this study, the following must apply to you:

  • You are a healthy adult male or female between 18 and 45 years of age, inclusive.
  • You do not have high blood pressure (hypertension).
  • If you are a woman you must not be pregnant, nor intend to become pregnant during the study.
  • You are not taking any regular systemic medication, other than the oral contraceptive pill.
  • At the screening visit you are willing for us to take your complete medical history and perform a physical examination.

About the studies

There are currently two different studies taking place (Study A and Study B), and you can choose to take part in either or both of them.

Each study requires three visits; an initial screening visit and then two follow up visits which will be at least seven days apart.

  • Study A will look at the handling of glucose
  • Study B will look at the handling of nitrate/nitrite levels

These will be done through blood, urine and saliva tests.

Participants will be paid for taking part.

Contact us

If you are interested in taking part and would like further detailed information to read or have any questions, please contact:

Dr Lidder at the Clinical Research Facility, St Thomas’ Hospital.

Tel: 020 7188 4925

Email: nitratestudies@gstt.nhs.uk 

These studies have been approved by South East London Research Ethics Committee 2 (10/H0802/52).

 

 
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